McCracken originally developed the show in 1992 as a cartoon short entitled Whoopass Stew! while in his second year at CalArts. Following a name change, Cartoon Network featured the first Powerpuff Girls pilots in its animation showcase program World Premiere Toons in 1995 and 1996. The series made its official debut as a Cartoon Cartoon on November 18, 1998, with the final episode airing on March 25, 2005. A total of 78 episodes were aired in addition to two shorts, a Christmas special, a feature film, a tenth anniversary special, and a special episode using CGI technology. Various spin-off media include an anime, three CD soundtracks, a home video collection, comic books, a series of video games, a 2016 reboot series, as well as various licensed merchandise. The series has been nominated for six Emmy Awards, nine Annie Awards, and a Kids’ Choice Award during its run.

Powerpuff girls coloring pages, These include various kinds of coloring books and, talking about the new generation, free printable coloring pages from the internet.